November 15th, 2026 – Morning Session
Location: McCormick Place, 2301 S Martin Luther King Dr., Chicago, IL 60616
Room: TBD

9:00 Welcome & Introduction
Organizers: XLOOP Chairs – Justin Wozniak, Nicholas Schwarz, Hannah Parraga
9:01 Session 1: Applying Scalable Computing to Scientific Data
Session Chair: TBD
9:01 Real-time Optimization of Simulation and Data Processing Pipelines for Experiments on Exascale Computing Platforms
Presenter: Thomas Wester
Authors: Thomas Wester, Harikrishna Tummalapalli, and Christine M. Simpson
9:17 DART: ML-Accelerated Surrogate for Real-Time CFD Digital Twins
Presenter: Shunyu Yao
Authors: Shunyu Yao, K. Todd Lowe, and Dimitrios S. Nikolopoulos
9:34 Fine-Tuning Foundation Models for Micro-CT Image Segmentation Using HPC Platforms
Presenter: Xiaoya Chong
Authors: Xiaoya Chong + 20
Artifacts Available
9:51 Short Talk: When Should Quantum and HPC Systems Be Co-Located? Lessons from Real-World Workflows
Presenter: Seetharami Seelam
10:00 Break
10:30 Session 2: Tightening the Experiment-Compute Loop
Session Chair: TBD
10:30 DRAVA: An Event-Driven Runtime for Scientific Pipelines with Agentic Configuration Optimization
Presenter: Venkateswaran Shekar
Authors: Venkateswaran Shekar, Yevgen Matviychuk, Eliot Gann, Daniel Allan
10:47 Building Resilient Self-Driving Laboratories with the INTERSECT Federated Ecosystem
Presenter: Christian Engelmann
Authors: Christian Engelmann, Andrew Ayres, Stephen DeWitt, Michael J. Brim, and Brett Eiffert
XLOOP Artifacts Available Badge Artifacts Available
11:04 Navigating the Spectrum of Science Workloads with ESnet JLab FPGA Accelerated Transport (EJ-FAT)
Presenter: Harinarayan Krishnan
Authors: Harinarayan Krishnan, Ronald J. Pandolfi, David A. Shapiro, Sophie A. Morley, and Yatish Kumar
11:21 Short Talk: Extending Advanced Photon Source Data Management System Workflows with Globus Streaming
Presenter: Siniša Veseli
11:30 Session 3: Advancing AI in Experiment Automation
Session Chair: TBD
11:30 Every State, Every Loop, All at Once: Reaching the Outer Loop of an Autonomous Laboratory
Presenter: Woong Shin
Authors: Woong Shin, Craig A. Bridges, Marshall T. McDonnell, Frédéric Suter, and Rafael Ferreira da Silva
11:47 Emblase: Using Tiled as an AI-Ready Data Access Service for Live Scientific Workflows
Presenter: Venkateswaran Shekar
Authors: Venkateswaran Shekar, Yevgen Matviychuk, Eliot Gann, and Daniel Allan
12:04 Exploring the Genesis Platform Capabilities to Accelerate Scientific Discovery in OPAL
Presenter: Venkateswaran Shekar
Authors: Daniel Rosendo, Renan Souza, Kelsey Carter, John Lagergren, Frédéric Suter, Shelaine L. Curd, David Weston, and Rafael Ferreira da Silva
12:21 Short Talk: Portable AI Workflows and Federated Agents for Experiment-in-the-Loop Synchrotron Science
Presenter: Tim J. Dunn
12:29 Awards Ceremony and Conclusion
Organizers: XLOOP Chairs – Justin Wozniak, Nicholas Schwarz, Hannah Parraga
12:30 Adjourn